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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A021400

Assay: viabilityTarget: KRASQC: ambiguous

Activity overview

IC50 = 100-1000 nM

TargetKRAS

Cell lineNCI-H358

Time5 d

Assay / ReadoutIC50 / viability

Assay IDPGDB_AS001442

PatentWO2025214350A1

QC statusambiguous

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C011622

CompoundExample 71

Source record IDPGDB_C011622

InChIKeyFNCHAYYCUNQLLD-PDBWILDYSA-N

Assay context

Assay IDPGDB_AS001442

Assay familyviability

Assay systemcell_based

ReadoutIC50

Treatment time5 d

Detection target% Cell viability

TargetKRAS

E3Not specified

Cell lineNCI-H358

OrganismHomo sapiens

Source evidence

Patent IDWO2025214350A1

Compound location

Example 71

Example 71 enlarged structure

Example 71 location on patent page 192

Activity table

Page 222 · table start

Page 223 · table middle

Page 224 · table middle

Page 225 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU