Assay

PGDB_AS001442

System: cell_basedCell line: NCI-H358
Assay context summary

Assay context

64 activity records
Assay familyviability
Systemcell_based
ReadoutIC50
E3Not specified
Cell lineNCI-H358
OrganismHomo sapiens
Detection target% Cell viability
Activity compounds and values

Activity records

64 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C011624
IC50-=1-10nM-—KRAS-NCI-H358WO2025214350A1PGDB_A009247PGDB_C011624PGDB_AS001442View
2D structure for PGDB_C011621
IC50-=100-1000nM-—KRAS-NCI-H358WO2025214350A1PGDB_A009873PGDB_C011621PGDB_AS001442View
2D structure for PGDB_C011632
IC50-<=1nM-—KRAS-NCI-H358WO2025214350A1PGDB_A010222PGDB_C011632PGDB_AS001442View
2D structure for PGDB_C011661
IC50-=1-10nM-—KRAS-NCI-H358WO2025214350A1PGDB_A010518PGDB_C011661PGDB_AS001442View
2D structure for PGDB_C011624
IC50-=1-10nM-—KRAS-NCI-H358WO2025214350A1PGDB_A010677PGDB_C011624PGDB_AS001442View
2D structure for PGDB_C011630
IC50-=1-10nM-—KRAS-NCI-H358WO2025214350A1PGDB_A012194PGDB_C011630PGDB_AS001442View
2D structure for PGDB_C011628
IC50-=1-10nM-—KRAS-NCI-H358WO2025214350A1PGDB_A012349PGDB_C011628PGDB_AS001442View
2D structure for PGDB_C011593
IC50-=1-10nM-—KRAS-NCI-H358WO2025214350A1PGDB_A014220PGDB_C011593PGDB_AS001442View
2D structure for PGDB_C011589
IC50-=1-10nM-—KRAS-NCI-H358WO2025214350A1PGDB_A014638PGDB_C011589PGDB_AS001442View
2D structure for PGDB_C011664
IC50-=1-10nM-—KRAS-NCI-H358WO2025214350A1PGDB_A017962PGDB_C011664PGDB_AS001442View
2D structure for PGDB_C011595
IC50-=1-10nM-—KRAS-NCI-H358WO2025214350A1PGDB_A019200PGDB_C011595PGDB_AS001442View
2D structure for PGDB_C011596
IC50-=1-10nM-—KRAS-NCI-H358WO2025214350A1PGDB_A019266PGDB_C011596PGDB_AS001442View
2D structure for PGDB_C011604
IC50-<=1nM-—KRAS-NCI-H358WO2025214350A1PGDB_A019469PGDB_C011604PGDB_AS001442View
2D structure for PGDB_C011658
IC50-=10-100nM-—KRAS-NCI-H358WO2025214350A1PGDB_A019500PGDB_C011658PGDB_AS001442View
2D structure for PGDB_C011622
IC50-=100-1000nM-—KRAS-NCI-H358WO2025214350A1PGDB_A021400PGDB_C011622PGDB_AS001442View
2D structure for PGDB_C011663
IC50-=1-10nM-—KRAS-NCI-H358WO2025214350A1PGDB_A021456PGDB_C011663PGDB_AS001442View
2D structure for PGDB_C011605
IC50-<=1nM-—KRAS-NCI-H358WO2025214350A1PGDB_A024336PGDB_C011605PGDB_AS001442View
2D structure for PGDB_C011637
IC50-=10-100nM-—KRAS-NCI-H358WO2025214350A1PGDB_A024669PGDB_C011637PGDB_AS001442View
2D structure for PGDB_C011617
IC50-=10-100nM-—KRAS-NCI-H358WO2025214350A1PGDB_A024861PGDB_C011617PGDB_AS001442View
2D structure for PGDB_C011611
IC50-=1-10nM-—KRAS-NCI-H358WO2025214350A1PGDB_A025956PGDB_C011611PGDB_AS001442View
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