Activity record

PGDB_A021626

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 1-10 nM

TargetGSPT1
Cell lineMV-4-11
Time72 h
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS001375
PatentWO2024222918A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C003262
Compound IDPGDB_C003262
Compound化合物B-1
Source record IDPGDB_C003262
InChIKeyLMOHLKQFJBXMCY-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001375
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineMV-4-11

Source evidence

Patent IDWO2024222918A1
Compound location

化合物B-1

化合物B-1 enlarged structure化合物B-1 location on patent page 47
Activity table
Page 53 · table single