Activity record

PGDB_A021898

Assay: % DegradationTarget: ESR1QC: ambiguous
Activity overview

IC50 = 0.9 nM

TargetESR1
Cell lineMCF-7
Time4 h
Assay / ReadoutIC50 / % Degradation
Assay IDPGDB_AS000996
PatentCN118984820A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C006906
Compound IDPGDB_C006906
Compound27
Source record IDPGDB_C006906
InChIKeyXBGSUODUYXQSHK-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000996
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Treatment time4 h
TargetESR1
E3Not specified
Cell lineMCF-7

Source evidence

Patent IDCN118984820A
Compound location

27

27 enlarged structure27 location on patent page 44
Activity table
Page 102 · table start
Page 103 · table end