Activity record

PGDB_A021947

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

GI50 < 100 nM

TargetGSPT1
Cell lineHL-60
Time48 h
Assay / Readoutluminescence / GI50
Assay IDPGDB_AS001555
PatentWO2023237116A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002229
Compound IDPGDB_C002229
CompoundExample 16
Source record IDPGDB_C002229
InChIKeyPFANWFNVGAICOQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001555
Assay familyviability
Assay systemcell_based
ReadoutGI50
Technologyluminescence
Treatment time48 h
Detection target% Cell viability
TargetGSPT1
E3Not specified
Cell lineHL-60

Source evidence

Patent IDWO2023237116A1
Compound location

Example 16

Example 16 enlarged structureExample 16 location on patent page 146
Activity table
Page 378 · table start
Page 379 · table end