Activity record

PGDB_A022356

Assay: % DegradationTarget: IKZF2QC: ambiguous
Activity overview

DC50 = 2.9 nM

TargetIKZF2
Cell lineJurkat
Time72 h
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS001637
PatentCN121487946A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007381
Compound IDPGDB_C007381
CompoundCOMPARATIVE COMPOUND A
Source record IDPGDB_C007381
InChIKeyOHSPSWUQMQUVMW-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001637
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Treatment time72 h
TargetIKZF2
E3Not specified
Cell lineJurkat

Source evidence

Patent IDCN121487946A
Compound location

COMPARATIVE COMPOUND A

COMPARATIVE COMPOUND A enlarged structureCOMPARATIVE COMPOUND A location on patent page 69
Activity table
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