Activity record

PGDB_A022404

Assay: bindingTarget: CRBNQC: ambiguous
Activity overview

EC50 = 0.018 uM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutEC50 / binding
Assay IDPGDB_AS001482
PatentUS20230265071A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000401
Compound IDPGDB_C000401
Compound51;51
Source record IDPGDB_C000401
InChIKeyDVMNBFKJAKDJAH-PFIFLBKHSA-N

Assay context

Assay IDPGDB_AS001482
Assay familybinding
Assay systembiochemical
ReadoutEC50
TargetCRBN
E3CRBN

Source evidence

Patent IDUS20230265071A1
Compound location

51;51

51;51 enlarged structure51;51 location on patent page 40
Activity table
Page 166 · table start
Page 167 · table middle
Page 168 · table middle
Page 169 · table end