Assay

PGDB_AS001482

System: biochemicalTarget: CRBN
Assay context summary

Assay context

99 activity records
Assay familybinding
Systembiochemical
ReadoutEC50
TargetCRBN
E3CRBN
Activity compounds and values

Activity records

99 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C000405
EC50-=0.239uM-—CRBNCRBN-US20230265071A1PGDB_A007218PGDB_C000405PGDB_AS001482View
2D structure for PGDB_C000397
EC50-=0.022uM-—CRBNCRBN-US20230265071A1PGDB_A007490PGDB_C000397PGDB_AS001482View
2D structure for PGDB_C000429
EC50-=0.921uM-—CRBNCRBN-US20230265071A1PGDB_A008205PGDB_C000429PGDB_AS001482View
2D structure for PGDB_C000406
EC50-=0.006uM-—CRBNCRBN-US20230265071A1PGDB_A008232PGDB_C000406PGDB_AS001482View
2D structure for PGDB_C000438
EC50->10uM-—CRBNCRBN-US20230265071A1PGDB_A008316PGDB_C000438PGDB_AS001482View
2D structure for PGDB_C004617
EC50-=0.02uM-—CRBNCRBN-US20230265071A1PGDB_A009485PGDB_C004617PGDB_AS001482View
2D structure for PGDB_C000435
EC50-=6.81uM-—CRBNCRBN-US20230265071A1PGDB_A009733PGDB_C000435PGDB_AS001482View
2D structure for PGDB_C000442
EC50-=0.042uM-—CRBNCRBN-US20230265071A1PGDB_A010658PGDB_C000442PGDB_AS001482View
2D structure for PGDB_C000399
EC50-=0.045uM-—CRBNCRBN-US20230265071A1PGDB_A010776PGDB_C000399PGDB_AS001482View
2D structure for PGDB_C000393
EC50-=0.044uM-—CRBNCRBN-US20230265071A1PGDB_A010814PGDB_C000393PGDB_AS001482View
2D structure for PGDB_C000416
EC50-=0.026uM-—CRBNCRBN-US20230265071A1PGDB_A010955PGDB_C000416PGDB_AS001482View
2D structure for PGDB_C000420
EC50-=0.007uM-—CRBNCRBN-US20230265071A1PGDB_A012606PGDB_C000420PGDB_AS001482View
2D structure for PGDB_C000443
EC50-=0.031uM-—CRBNCRBN-US20230265071A1PGDB_A013060PGDB_C000443PGDB_AS001482View
2D structure for PGDB_C000414
EC50-=0.024uM-—CRBNCRBN-US20230265071A1PGDB_A013098PGDB_C000414PGDB_AS001482View
2D structure for PGDB_C000471
EC50-=0.014uM-—CRBNCRBN-US20230265071A1PGDB_A014811PGDB_C000471PGDB_AS001482View
2D structure for PGDB_C000412
EC50-=0.015uM-—CRBNCRBN-US20230265071A1PGDB_A014900PGDB_C000412PGDB_AS001482View
2D structure for PGDB_C000392
EC50-=0.025uM-—CRBNCRBN-US20230265071A1PGDB_A014929PGDB_C000392PGDB_AS001482View
2D structure for PGDB_C000411
EC50-=0.046uM-—CRBNCRBN-US20230265071A1PGDB_A015140PGDB_C000411PGDB_AS001482View
2D structure for PGDB_C000452
EC50-=0.019uM-—CRBNCRBN-US20230265071A1PGDB_A015259PGDB_C000452PGDB_AS001482View
2D structure for PGDB_C000394
EC50-=0.011uM-—CRBNCRBN-US20230265071A1PGDB_A015863PGDB_C000394PGDB_AS001482View
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