Activity record

PGDB_A022497

Assay: % DegradationQC: ambiguous
Activity overview

EC50 = 0.057 uM

Cell line293GT
Time14 h
Assay / Readoutluminescence / EC50
Assay IDPGDB_AS001169
PatentCN111051298A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C022730
Compound IDPGDB_C022730
CompoundI-134
Source record IDPGDB_C022730
InChIKeyXJNINVLKRMVWLF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001169
Assay family% Degradation
Assay systemcell_based
ReadoutEC50
Technologyluminescence
Treatment time14 h
Detection targetprotein_degradation
TargetIKZF2
E3CRBN
Cell line293GT
OrganismHomo sapiens

Source evidence

Patent IDCN111051298A
Compound location

I-134

multi-compoundsneed check
Activity table
Page 235 · table start
Page 236 · table middle
Page 237 · table middle
Page 238 · table middle
Page 239 · table end