Activity record

PGDB_A022588

Assay: % DegradationTarget: CDK12QC: ambiguous
Activity overview

IC50 <= 0.1 uM

TargetCDK12
Assay / ReadoutIC50 / % Degradation
Assay IDPGDB_AS002095
PatentWO2025110815A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010958
Compound IDPGDB_C010958
Compound75
Source record IDPGDB_C010958
InChIKeyPMBLXEOZBCTNNL-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002095
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
TargetCDK12
E3Not specified

Source evidence

Patent IDWO2025110815A1
Compound location

75

75 enlarged structure75 location on patent page 116
Activity table
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