Activity record

PGDB_A022645

Assay: % DegradationTarget: ESR1QC: ambiguous
Activity overview

IC50 = 0.89 nM

TargetESR1
Cell lineMCF-7
Time24 h
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS001594
PatentCN115260206A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C006613
Compound IDPGDB_C006613
Compound实施例1
Source record IDPGDB_C006613
InChIKeyIGYKTXJZWRSDLK-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001594
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Technologyfluorescence
Treatment time24 h
Detection targetprotein_degradation
TargetESR1
E3Not specified
Cell lineMCF-7

Source evidence

Patent IDCN115260206A
Compound location

实施例1

实施例1 enlarged structure实施例1 location on patent page 23
Activity table
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