Activity record

PGDB_A022677

Assay: % DegradationTarget: VHLQC: standardized
Activity overview

degradation = 80 %

TargetVHL
Cell lineSH-SY5Y
Concentration1 uM
Time24 h
Assay / ReadoutWestern_blot / % Degradation
Assay IDPGDB_AS001892
PatentCN119613482A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C006925
Compound IDPGDB_C006925
CompoundI-2;I-2
Source record IDPGDB_C006925
InChIKeyKHXMEYUTLVQWBB-ONBPZOJHSA-N

Assay context

Assay IDPGDB_AS001892
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
TechnologyWestern_blot
Concentration1 uM
Treatment time24 h
Detection targetprotein_degradation
TargetVHL
E3Not specified
Cell lineSH-SY5Y

Source evidence

Patent IDCN119613482A
Compound location

I-2;I-2

I-2;I-2 enlarged structureI-2;I-2 location on patent page 3
Activity table
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