Activity record

PGDB_A023036

Assay: % DegradationTarget: IKZF3QC: standardized
Activity overview

degradation = 87 %

TargetIKZF3
Cell lineH929
Concentration20 uM
Time24 h
Assay / ReadoutWestern_blot / % Degradation
Assay IDPGDB_AS001985
PatentCN116457344A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009601
Compound IDPGDB_C009601
CompoundPomalidomide
Source record IDPGDB_C000056
InChIKeyUVSMNLNDYGZFPF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001985
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
TechnologyWestern_blot
Concentration20 uM
Treatment time24 h
Detection targetprotein_degradation
TargetIKZF3
E3Not specified
Cell lineH929

Source evidence

Patent IDCN116457344A
Compound location

Pomalidomide

Pomalidomide enlarged structurePomalidomide location on patent page 85
Activity table
Page 95 · table single