Activity record

PGDB_A023054

Assay: % DegradationTarget: IKZF1QC: standardized
Activity overview

DC50 = 0.025 nM

TargetIKZF1
Cell lineHT-1080
Time20 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001653
PatentEP4393915A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007543
Compound IDPGDB_C007543
Compound化合物 1;化合物 1
Source record IDPGDB_C007543
InChIKeyKZKHPBKQIYRQPI-SYQKMTEESA-N

Assay context

Assay IDPGDB_AS001653
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time20 h
Detection targetprotein_degradation
TargetIKZF1
E3Not specified
Cell lineHT-1080
OrganismHomo sapiens

Source evidence

Patent IDEP4393915A1
Compound location

化合物 1;化合物 1

化合物 1;化合物 1 enlarged structure化合物 1;化合物 1 location on patent page 102
Activity table
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