Activity record

PGDB_A023172

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

Dmax = 82 %

TargetNEK7
E3 ligaseCRBN
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS001956
PatentWO2025024521A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020439
Compound IDPGDB_C020439
Compound266
Source record IDPGDB_C016569
InChIKeyLMSNQEBHCGVTKQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001956
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
TargetNEK7
E3CRBN

Source evidence

Patent IDWO2025024521A1
Compound location

266

266 enlarged structure266 location on patent page 87
Activity table
Page 416 · table single