Activity record

PGDB_A023373

Assay: % DegradationTarget: GSPT1QC: manual_curated
Activity overview

EC50 = <= 0.5 nM

TargetGSPT1
Time24 h
Assay / Readoutfluorescence / EC50
Assay IDPGDB_AS002258
PatentWO2025162410A1
QC statusmanual_curated
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020495
Compound IDPGDB_C020495
Compound3-5-5;3-5-5
Source record IDPGDB_C020495
InChIKeyJORWIEUPJCHDFC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002258
Assay family% Degradation
Assay systemcell_based
ReadoutEC50
Technologyfluorescence
Treatment time24 h
TargetGSPT1
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025162410A1
Compound location

3-5-5;3-5-5

3-5-5;3-5-5 enlarged structure3-5-5;3-5-5 location on patent page 31
Activity table
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