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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A023565

Assay: % DegradationTarget: GSPT1QC: ambiguous

Activity overview

degradation >= 80 %

TargetGSPT1

Cell lineKG-1

Concentration200 nM

Time4 h

Assay / ReadoutWestern_blot / % Degradation

Assay IDPGDB_AS000482

PatentWO2024222918A1

QC statusambiguous

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C003248

Compound化合物A-21

Source record IDPGDB_C003248

InChIKeyGBMLGLBBNNBKFK-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000482

Assay family% Degradation

Assay systemcell_based

Readout% Degradation

TechnologyWestern_blot

Concentration200 nM

Treatment time4 h

Detection targetprotein_degradation

TargetGSPT1

E3Not specified

Cell lineKG-1

Source evidence

Patent IDWO2024222918A1

Compound location

化合物A-21

化合物A-21 enlarged structure

化合物A-21 location on patent page 35

Activity table

Page 50 · table start

Page 51 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU