Activity record

PGDB_A023945

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

Dmax = 71 %

TargetGSPT1
Cell lineNB4
Time4 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS000251
PatentWO2024222614A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C003179
Compound IDPGDB_C003179
Compound5;5
Source record IDPGDB_C003179
InChIKeyZVFMNRXJCWUPDY-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000251
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Treatment time4 h
Detection targetprotein_degradation
TargetGSPT1
E3Not specified
Cell lineNB4

Source evidence

Patent IDWO2024222614A1
Compound location

5;5

5;5 enlarged structure5;5 location on patent page 10
Activity table
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