Activity record

PGDB_A024058

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

DC50 = 936 nM

TargetGSPT1
Cell lineHEK293
Time72 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS000381
PatentIL323841A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008161
Compound IDPGDB_C008161
Compound10
Source record IDPGDB_C008161
InChIKeyPXSOKLASZRTKJZ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000381
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time72 h
Detection targetprotein_degradation
TargetGSPT1
E3Not specified
Cell lineHEK293
OrganismHomo sapiens

Source evidence

Patent IDIL323841A
Compound location

10

10 enlarged structure10 location on patent page 52
Activity table
Page 59 · table start
Page 60 · table end