Assay

PGDB_AS000381

System: cell_basedTarget: GSPT1Cell line: HEK293
Assay context summary

Assay context

22 activity records
Assay family% Degradation
Systemcell_based
ReadoutDC50
TargetGSPT1
E3Not specified
Cell lineHEK293
OrganismHomo sapiens
Technologyluminescence
Detection targetprotein_degradation
Activity compounds and values

Activity records

22 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C019545
DC50->10000nM-—GSPT1-HEK293IL323841APGDB_A013017PGDB_C019545PGDB_AS000381View
2D structure for PGDB_C008163
DC50-=751nM-—GSPT1-HEK293IL323841APGDB_A015410PGDB_C008163PGDB_AS000381View
2D structure for PGDB_C008154
DC50->10000nM-—GSPT1-HEK293IL323841APGDB_A017290PGDB_C008154PGDB_AS000381View
2D structure for PGDB_C008161
DC50-=936nM-—GSPT1-HEK293IL323841APGDB_A024058PGDB_C008161PGDB_AS000381View
2D structure for PGDB_C008160
DC50->10000nM-—GSPT1-HEK293IL323841APGDB_A026363PGDB_C008160PGDB_AS000381View
2D structure for PGDB_C008158
DC50->10000nM-—GSPT1-HEK293IL323841APGDB_A030209PGDB_C008158PGDB_AS000381View
2D structure for PGDB_C008166
DC50-=318nM-—GSPT1-HEK293IL323841APGDB_A034929PGDB_C008166PGDB_AS000381View
2D structure for PGDB_C008150
DC50-=1712.9nM-—GSPT1-HEK293IL323841APGDB_A036505PGDB_C008150PGDB_AS000381View
2D structure for PGDB_C008153
DC50-=129nM-—GSPT1-HEK293IL323841APGDB_A036978PGDB_C008153PGDB_AS000381View
2D structure for PGDB_C008159
DC50-=3090nM-—GSPT1-HEK293IL323841APGDB_A037210PGDB_C008159PGDB_AS000381View
2D structure for PGDB_C008165
DC50-=118nM-—GSPT1-HEK293IL323841APGDB_A037646PGDB_C008165PGDB_AS000381View
2D structure for PGDB_C008152
DC50-=495.8nM-—GSPT1-HEK293IL323841APGDB_A038633PGDB_C008152PGDB_AS000381View
2D structure for PGDB_C008164
DC50-=399nM-—GSPT1-HEK293IL323841APGDB_A039798PGDB_C008164PGDB_AS000381View
2D structure for PGDB_C008167
DC50-=218nM-—GSPT1-HEK293IL323841APGDB_A054432PGDB_C008167PGDB_AS000381View
2D structure for PGDB_C008168
DC50-=104nM-—GSPT1-HEK293IL323841APGDB_A054895PGDB_C008168PGDB_AS000381View
2D structure for PGDB_C008151
DC50-=214nM-—GSPT1-HEK293IL323841APGDB_A055127PGDB_C008151PGDB_AS000381View
2D structure for PGDB_C008149
DC50-=557.1nM-—GSPT1-HEK293IL323841APGDB_A060375PGDB_C008149PGDB_AS000381View
2D structure for PGDB_C008157
DC50-=131nM-—GSPT1-HEK293IL323841APGDB_A062474PGDB_C008157PGDB_AS000381View
2D structure for PGDB_C008162
DC50-=2953.8nM-—GSPT1-HEK293IL323841APGDB_A065065PGDB_C008162PGDB_AS000381View
2D structure for PGDB_C001361
DC50-=454.5nM-—GSPT1-HEK293IL323841APGDB_A071133PGDB_C001361PGDB_AS000381View
Page 1 of 2 · 22 records