Activity record

PGDB_A024060

Assay: % DegradationTarget: IKZF3QC: ambiguous
Activity overview

DC50 = 26 nM

TargetIKZF3
Time24 h
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS001957
PatentUS20250129061A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009145
Compound IDPGDB_C009145
Compound2
Source record IDPGDB_C009145
InChIKeyPKEKMIKJWMHBLO-HXVTVHMQSA-N

Assay context

Assay IDPGDB_AS001957
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Treatment time24 h
TargetIKZF3
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDUS20250129061A1
Compound location

2

2 enlarged structure2 location on patent page 71
Activity table
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