Activity record

PGDB_A024109

Assay: viabilityTarget: IKZF3QC: ambiguous
Activity overview

inhibition = 10-15 %

TargetIKZF3
Cell lineKasumi-1
Concentration10 nM
Assay / Readout% Inhibition / viability
Assay IDPGDB_AS001962
PatentWO2025016359A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019527
Compound IDPGDB_C019527
CompoundGT-08134
Source record IDPGDB_C019527
InChIKeyFGSJAAAWJQDPSZ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001962
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Concentration10 nM
Detection target% Cell viability
TargetIKZF3
E3Not specified
Cell lineKasumi-1
OrganismHomo sapiens

Source evidence

Patent IDWO2025016359A1
Compound location

GT-08134

GT-08134 enlarged structureGT-08134 location on patent page 50
Activity table
Page 199 · table single