Activity record

PGDB_A024187

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

EC50 = 0.12 uM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutHTRF / EC50
Assay IDPGDB_AS000405
PatentWO2025024521A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020439
Compound IDPGDB_C020439
Compound266
Source record IDPGDB_C016569
InChIKeyLMSNQEBHCGVTKQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000405
Assay familybiochemical
Assay systembiochemical
ReadoutEC50
TechnologyHTRF
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2025024521A1
Compound location

266

266 enlarged structure266 location on patent page 87
Activity table
Page 416 · table single