Assay

PGDB_AS000405

System: biochemicalTarget: CRBN
Assay context summary

Assay context

19 activity records
Assay familybiochemical
Systembiochemical
ReadoutEC50
TargetCRBN
E3CRBN
TechnologyHTRF
Activity compounds and values

Activity records

19 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C020451
EC50-=0.19uM-—CRBNCRBN-WO2025024521A1PGDB_A010082PGDB_C020451PGDB_AS000405View
2D structure for PGDB_C020444
EC50-=0.52uM-—CRBNCRBN-WO2025024521A1PGDB_A012430PGDB_C020444PGDB_AS000405View
2D structure for PGDB_C020447
EC50-=10uM-—CRBNCRBN-WO2025024521A1PGDB_A017923PGDB_C020447PGDB_AS000405View
2D structure for PGDB_C020446
EC50-=0.25uM-—CRBNCRBN-WO2025024521A1PGDB_A020548PGDB_C020446PGDB_AS000405View
2D structure for PGDB_C020439
EC50-=0.12uM-—CRBNCRBN-WO2025024521A1PGDB_A024187PGDB_C020439PGDB_AS000405View
2D structure for PGDB_C020450
EC50-=0.18uM-—CRBNCRBN-WO2025024521A1PGDB_A026127PGDB_C020450PGDB_AS000405View
2D structure for PGDB_C020453
EC50-=0.29uM-—CRBNCRBN-WO2025024521A1PGDB_A028490PGDB_C020453PGDB_AS000405View
2D structure for PGDB_C020449
EC50-=0.19uM-—CRBNCRBN-WO2025024521A1PGDB_A030231PGDB_C020449PGDB_AS000405View
2D structure for PGDB_C020438
EC50-=0.12uM-—CRBNCRBN-WO2025024521A1PGDB_A038923PGDB_C020438PGDB_AS000405View
2D structure for PGDB_C020436
EC50-=0.1uM-—CRBNCRBN-WO2025024521A1PGDB_A041097PGDB_C020436PGDB_AS000405View
2D structure for PGDB_C020437
EC50-=0.13uM-—CRBNCRBN-WO2025024521A1PGDB_A042212PGDB_C020437PGDB_AS000405View
2D structure for PGDB_C020455
EC50-=0.11uM-—CRBNCRBN-WO2025024521A1PGDB_A046950PGDB_C020455PGDB_AS000405View
2D structure for PGDB_C020440
EC50-=0.11uM-—CRBNCRBN-WO2025024521A1PGDB_A054430PGDB_C020440PGDB_AS000405View
2D structure for PGDB_C020454
EC50-=0.26uM-—CRBNCRBN-WO2025024521A1PGDB_A057406PGDB_C020454PGDB_AS000405View
2D structure for PGDB_C020442
EC50-=0.1uM-—CRBNCRBN-WO2025024521A1PGDB_A059074PGDB_C020442PGDB_AS000405View
2D structure for PGDB_C020435
EC50-=0.08uM-—CRBNCRBN-WO2025024521A1PGDB_A059101PGDB_C020435PGDB_AS000405View
2D structure for PGDB_C020448
EC50-=0.21uM-—CRBNCRBN-WO2025024521A1PGDB_A059861PGDB_C020448PGDB_AS000405View
2D structure for PGDB_C020452
EC50-=0.35uM-—CRBNCRBN-WO2025024521A1PGDB_A060396PGDB_C020452PGDB_AS000405View
2D structure for PGDB_C020445
EC50-=0.23uM-—CRBNCRBN-WO2025024521A1PGDB_A073899PGDB_C020445PGDB_AS000405View
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