Activity record

PGDB_A024343

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 < 1 uM

TargetCRBN
E3 ligaseCRBN
Time1 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS001130
PatentUS12540127B2
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009039
Compound IDPGDB_C009039
CompoundI-62;I-62
Source record IDPGDB_C009039
InChIKeyCSZPGTRROXXITP-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001130
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time1 h
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDUS12540127B2
Compound location

I-62;I-62

I-62;I-62 enlarged structureI-62;I-62 location on patent page 56
Activity table
Page 175 · table single