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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A024357

Assay: % DegradationTarget: IKZF3QC: standardized

Activity overview

degradation < 50 %

TargetIKZF3

ConcentrationConcentration context: 500 nM

Time24 h

Assay / ReadoutWestern_blot / % Degradation

Assay IDPGDB_AS000176

PatentWO2024032689A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C002645

CompoundGT-05644

Source record IDPGDB_C002645

InChIKeyYBNKJQMFHJHHCL-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000176

Assay family% Degradation

Assay systemcell_based

Readout% Degradation

TechnologyWestern_blot

ConcentrationConcentration context: 500 nM

Treatment time24 h

Detection targetprotein_degradation

TargetIKZF3

E3Not specified

OrganismHomo sapiens

Source evidence

Patent IDWO2024032689A1

Compound location

GT-05644

GT-05644 enlarged structure

GT-05644 location on patent page 60

Activity table

Page 250 · table start

Page 251 · table middle

Page 252 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU