PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

138 activity records

Assay family% Degradation

Systemcell_based

Readout% Degradation

TargetIKZF3

E3Not specified

OrganismHomo sapiens

TechnologyWestern_blot

Detection targetprotein_degradation

Activity compounds and values

Activity records

138 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A007888	PGDB_C002534	PGDB_AS000176	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A008508	PGDB_C002592	PGDB_AS000176	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A008921	PGDB_C002531	PGDB_AS000176	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A009285	PGDB_C002782	PGDB_AS000176	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A009556	PGDB_C002571	PGDB_AS000176	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A009804	PGDB_C002584	PGDB_AS000176	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A009889	PGDB_C002725	PGDB_AS000176	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A010134	PGDB_C002734	PGDB_AS000176	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A011784	PGDB_C002564	PGDB_AS000176	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A012824	PGDB_C002675	PGDB_AS000176	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A013119	PGDB_C002559	PGDB_AS000176	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A013544	PGDB_C002509	PGDB_AS000176	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A013760	PGDB_C002576	PGDB_AS000176	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A014252	PGDB_C002527	PGDB_AS000176	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A015001	PGDB_C002756	PGDB_AS000176	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A015749	PGDB_C002783	PGDB_AS000176	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A016032	PGDB_C002519	PGDB_AS000176	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A016083	PGDB_C002535	PGDB_AS000176	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A016956	PGDB_C002572	PGDB_AS000176	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	IKZF3	-	-	WO2024032689A1	PGDB_A017022	PGDB_C002522	PGDB_AS000176	View

Rows per pagePage 1 of 7 · 138 recordsGo to page