Activity record

PGDB_A024718

Assay: viabilityTarget: CCNKQC: ambiguous
Activity overview

GI50 > 3000 nM

TargetCCNK
Cell lineTHP-1
Time144 h
Assay / Readoutluminescence / GI50
Assay IDPGDB_AS002373
PatentWO2025245472A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C012018
Compound IDPGDB_C012018
Compound153;153
Source record IDPGDB_C012018
InChIKeyULHYBMKFOUTNTA-YLQYIJTPSA-N

Assay context

Assay IDPGDB_AS002373
Assay familyviability
Assay systemcell_based
ReadoutGI50
Technologyluminescence
Treatment time144 h
Detection targetprotein_degradation
TargetCCNK
E3Not specified
Cell lineTHP-1
OrganismHomo sapiens

Source evidence

Patent IDWO2025245472A1
Compound location

153;153

153;153 enlarged structure153;153 location on patent page 78
Activity table
Page 220 · table start
Page 221 · table end