Activity record

PGDB_A024771

Assay: % DegradationTarget: CDK2QC: ambiguous
Activity overview

Dmax = 26 %

TargetCDK2
Cell lineHEK293
Concentration10 uM
Time18 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS001468
PatentWO2025043225
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007961
Compound IDPGDB_C007961
Compound30;30;30
Source record IDPGDB_C007961
InChIKeyHXTVMAZFDZYWEL-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001468
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Concentration10 uM
Treatment time18 h
TargetCDK2
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

30;30;30

30;30;30 enlarged structure30;30;30 location on patent page 22
Activity table
Page 525 · table start
Page 526 · table end