Activity record

PGDB_A024780

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 = 0.016 uM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutIC50 / binding
Assay IDPGDB_AS000958
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008042
Compound IDPGDB_C008042
Compound61;61;61;61
Source record IDPGDB_C008042
InChIKeyZUKCQYDLNHODJJ-XEWABKELSA-N

Assay context

Assay IDPGDB_AS000958
Assay familybinding
Assay systembiochemical
ReadoutIC50
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2025043225
Compound location

61;61;61;61

61;61;61;61 enlarged structure61;61;61;61 location on patent page 40
Activity table
Page 528 · table start
Page 529 · table end