Assay

PGDB_AS000958

System: biochemicalTarget: CRBN
Assay context summary

Assay context

21 activity records
Assay familybinding
Systembiochemical
ReadoutIC50
TargetCRBN
E3CRBN
Activity compounds and values

Activity records

21 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C008031
IC50-=0.044uM-—CRBNCRBN-WO2025043225PGDB_A013965PGDB_C008031PGDB_AS000958View
2D structure for PGDB_C008040
IC50-=0.021uM-—CRBNCRBN-WO2025043225PGDB_A017157PGDB_C008040PGDB_AS000958View
2D structure for PGDB_C008027
IC50-=0.041uM-—CRBNCRBN-WO2025043225PGDB_A018932PGDB_C008027PGDB_AS000958View
2D structure for PGDB_C008042
IC50-=0.016uM-—CRBNCRBN-WO2025043225PGDB_A024780PGDB_C008042PGDB_AS000958View
2D structure for PGDB_C008044
IC50-=0.017uM-—CRBNCRBN-WO2025043225PGDB_A025103PGDB_C008044PGDB_AS000958View
2D structure for PGDB_C008033
IC50-=0.028uM-—CRBNCRBN-WO2025043225PGDB_A025123PGDB_C008033PGDB_AS000958View
2D structure for PGDB_C008024
IC50-=0.056uM-—CRBNCRBN-WO2025043225PGDB_A025414PGDB_C008024PGDB_AS000958View
2D structure for PGDB_C008030
IC50-=0.012uM-—CRBNCRBN-WO2025043225PGDB_A027114PGDB_C008030PGDB_AS000958View
2D structure for PGDB_C008025
IC50-=0.028uM-—CRBNCRBN-WO2025043225PGDB_A030685PGDB_C008025PGDB_AS000958View
2D structure for PGDB_C008023
IC50-=0.033uM-—CRBNCRBN-WO2025043225PGDB_A037448PGDB_C008023PGDB_AS000958View
2D structure for PGDB_C008043
IC50-=0.078uM-—CRBNCRBN-WO2025043225PGDB_A037728PGDB_C008043PGDB_AS000958View
2D structure for PGDB_C008021
IC50-=0.016uM-—CRBNCRBN-WO2025043225PGDB_A044347PGDB_C008021PGDB_AS000958View
2D structure for PGDB_C008041
IC50-=0.12uM-—CRBNCRBN-WO2025043225PGDB_A045833PGDB_C008041PGDB_AS000958View
2D structure for PGDB_C008032
IC50-=0.11uM-—CRBNCRBN-WO2025043225PGDB_A045846PGDB_C008032PGDB_AS000958View
2D structure for PGDB_C008026
IC50-=0.038uM-—CRBNCRBN-WO2025043225PGDB_A051606PGDB_C008026PGDB_AS000958View
2D structure for PGDB_C008045
IC50-=0.065uM-—CRBNCRBN-WO2025043225PGDB_A052278PGDB_C008045PGDB_AS000958View
2D structure for PGDB_C008028
IC50-=0.051uM-—CRBNCRBN-WO2025043225PGDB_A053456PGDB_C008028PGDB_AS000958View
2D structure for PGDB_C008022
IC50-=0.02uM-—CRBNCRBN-WO2025043225PGDB_A071687PGDB_C008022PGDB_AS000958View
2D structure for PGDB_C008020
IC50-=0.043uM-—CRBNCRBN-WO2025043225PGDB_A072631PGDB_C008020PGDB_AS000958View
2D structure for PGDB_C008034
IC50-=0.71uM-—CRBNCRBN-WO2025043225PGDB_A076050PGDB_C008034PGDB_AS000958View
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