Activity record

PGDB_A024902

Assay: % DegradationTarget: IKZF3QC: ambiguous
Activity overview

DC50 = 600 nM

TargetIKZF3
Cell lineJurkat
Time24 h
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS000098
PatentWO2025049840
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010125
Compound IDPGDB_C010125
CompoundEXAMPLE 1
Source record IDPGDB_C010125
InChIKeyZMLKQUYYZBYSNQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000098
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Treatment time24 h
TargetIKZF3
E3Not specified
Cell lineJurkat
OrganismHomo sapiens

Source evidence

Patent IDWO2025049840
Compound location

EXAMPLE 1

EXAMPLE 1 enlarged structureEXAMPLE 1 location on patent page 81
Activity table
Page 104 · table single