Activity record

PGDB_A025820

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

Dmax = 3 %

TargetNEK7
E3 ligaseCRBN
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS001956
PatentWO2025024521A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020447
Compound IDPGDB_C020447
Compound274;274
Source record IDPGDB_C016577
InChIKeyBNYNSHQSTACUTA-QFIPXVFZSA-N

Assay context

Assay IDPGDB_AS001956
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
TargetNEK7
E3CRBN

Source evidence

Patent IDWO2025024521A1
Compound location

274;274

274;274 enlarged structure274;274 location on patent page 88
Activity table
Page 416 · table single