Activity record

PGDB_A025974

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

degradation = 53 %

TargetGSPT1
Cell lineHL-60
Concentration10 nM
Time24 h
Assay / ReadoutWestern_blot / percent_remaining
Assay IDPGDB_AS000871
PatentWO2023116835A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001985
Compound IDPGDB_C001985
CompoundA140;A140;A140
Source record IDPGDB_C001985
InChIKeyOCXWNXJTKGJZPR-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000871
Assay family% Degradation
Assay systemcell_based
Readoutpercent_remaining
TechnologyWestern_blot
Concentration10 nM
Treatment time24 h
TargetGSPT1
E3Not specified
Cell lineHL-60

Source evidence

Patent IDWO2023116835A1
Compound location

A140;A140;A140

A140;A140;A140 enlarged structureA140;A140;A140 location on patent page 56
Activity table
Page 141 · table single