PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

38 activity records

Assay family% Degradation

Systemcell_based

Readoutpercent_remaining

TargetGSPT1

E3Not specified

Cell lineHL-60

TechnologyWestern_blot

Activity compounds and values

Activity records

38 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	=	100	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A010369	PGDB_C000644	PGDB_AS000871	View
% Degradation	-	=	93	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A012580	PGDB_C000639	PGDB_AS000871	View
% Degradation	-	=	100	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A015702	PGDB_C000626	PGDB_AS000871	View
% Degradation	-	=	95	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A016349	PGDB_C000555	PGDB_AS000871	View
% Degradation	-	=	99	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A019104	PGDB_C000641	PGDB_AS000871	View
% Degradation	-	=	98	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A023984	PGDB_C000645	PGDB_AS000871	View
% Degradation	-	=	53	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A025974	PGDB_C001985	PGDB_AS000871	View
% Degradation	-	=	100	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A026794	PGDB_C000617	PGDB_AS000871	View
% Degradation	-	=	84	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A026913	PGDB_C000540	PGDB_AS000871	View
% Degradation	-	=	98	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A028552	PGDB_C000612	PGDB_AS000871	View
% Degradation	-	=	96	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A029440	PGDB_C000554	PGDB_AS000871	View
% Degradation	-	=	100	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A031160	PGDB_C000606	PGDB_AS000871	View
% Degradation	-	=	100	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A032888	PGDB_C000607	PGDB_AS000871	View
% Degradation	-	=	97	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A033069	PGDB_C000541	PGDB_AS000871	View
% Degradation	-	=	100	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A034128	PGDB_C000610	PGDB_AS000871	View
% Degradation	-	=	77	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A036428	PGDB_C000562	PGDB_AS000871	View
% Degradation	-	=	95	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A039726	PGDB_C000556	PGDB_AS000871	View
% Degradation	-	=	100	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A041971	PGDB_C000616	PGDB_AS000871	View
% Degradation	-	=	47	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A046009	PGDB_C000561	PGDB_AS000871	View
% Degradation	-	=	94	%	10 nM	24 h	GSPT1	-	HL-60	WO2023116835A1	PGDB_A046376	PGDB_C000643	PGDB_AS000871	View

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