Activity record

PGDB_A026196

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

potency_ratio = 10-20 fold

TargetGSPT1
Cell lineGP2D
Time72 h
ControlRef1
Assay / ReadoutCCK-8 / Fold change
Assay IDPGDB_AS001306
PatentWO2025026218A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005376
Compound IDPGDB_C005376
Compound化合物 C005;化合物 C005
Source record IDPGDB_C005376
InChIKeyQXDIIFLYKMIBCL-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001306
Assay familyviability
Assay systemcell_based
ReadoutFold change
TechnologyCCK-8
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineGP2D
OrganismHomo sapiens

Source evidence

Patent IDWO2025026218A1
Compound location

化合物 C005;化合物 C005

化合物 C005;化合物 C005 enlarged structure化合物 C005;化合物 C005 location on patent page 33
Activity table
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