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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU

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·

SIMM · NJU

Activity record

PGDB_A026859

Assay: % DegradationQC: standardized

Activity overview

Emax > 60 %

Cell line293T.114

TimeDC50 > 10000 nM | > 100 nM | DC50 < 100 nM

Assay / Readoutluminescence / Emax

Assay IDPGDB_AS000287

PatentWO2022081927A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C016650

Compound177

Source record IDPGDB_C026781

InChIKeyIYWHTEBGBSZIFM-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000287

Assay family% Degradation

Assay systemcell_based

ReadoutEmax

Technologyluminescence

Treatment timeDC50 > 10000 nM | > 100 nM | DC50 < 100 nM

TargetGSPT1

E3Not specified

Cell line293T.114

OrganismHomo sapiens

Source evidence

Patent IDWO2022081927A1

Compound location

177

177 enlarged structure

177 location on patent page 535

Activity table

Page 529 · table start

Page 530 · table middle

Page 531 · table middle

Page 532 · table middle

Page 533 · table middle

Page 534 · table middle

Page 535 · table middle

Page 536 · table middle

Page 537 · table middle

Page 538 · table middle

Page 539 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU