Activity record

PGDB_A026962

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

Dmax > 75 %

TargetNEK7
E3 ligaseCRBN
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS002165
PatentWO2025024521A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020247
Compound IDPGDB_C020247
Compound74
Source record IDPGDB_C016377
InChIKeyHJUURZMTOYGOOA-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002165
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
TargetNEK7
E3CRBN

Source evidence

Patent IDWO2025024521A1
Compound location

74

74 enlarged structure74 location on patent page 79
Activity table
Page 416 · table start
Page 417 · table middle
Page 418 · table end