Activity record

PGDB_A027509

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 246.58 nM

TargetCRBN
E3 ligaseCRBN
Time15 min
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000570
PatentCN118852145A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001460
Compound IDPGDB_C001460
Compound实施例9
Source record IDPGDB_C001460
InChIKeyFTGOOYXLOHVAGZ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000570
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time15 min
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDCN118852145A
Compound location

实施例9

实施例9 enlarged structure实施例9 location on patent page 38
Activity table
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