Activity record

PGDB_A027717

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

IC50 = 10 uM

TargetGSPT1
Cell lineHEK293
Time6 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS002511
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007982
Compound IDPGDB_C007982
Compound77;77
Source record IDPGDB_C007982
InChIKeyYLLDWBRIXXXQLA-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002511
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time6 h
TargetGSPT1
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

77;77

77;77 enlarged structure77;77 location on patent page 24
Activity table
Page 527 · table start
Page 528 · table end