Activity record

PGDB_A027912

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

EC50 < 100 nM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutHTRF / EC50
Assay IDPGDB_AS000488
PatentWO2025024521A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020432
Compound IDPGDB_C020432
Compound259.0
Source record IDPGDB_C016562
InChIKeyFKWWNEAGZWUXOB-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000488
Assay familybiochemical
Assay systembiochemical
ReadoutEC50
TechnologyHTRF
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2025024521A1
Compound location

259.0

259.0 enlarged structure259.0 location on patent page 87
Activity table
Page 416 · table start
Page 417 · table middle
Page 418 · table end