Activity record

PGDB_A027931

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 10-30 nM

TargetGSPT1
Cell lineBT-474
Time6 d
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001477
PatentCN121219280A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001019
Compound IDPGDB_C001019
Compound1;实施例1
Source record IDPGDB_C001019
InChIKeyMHNFNBKLPVSPTK-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001477
Assay familyviability
Assay systemcell_based
ReadoutIC50
Treatment time6 d
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineBT-474

Source evidence

Patent IDCN121219280A
Compound location

1;实施例1

1;实施例1 enlarged structure1;实施例1 location on patent page 19
Activity table
Page 34 · table single