PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberCN121219280A

AssigneeYinen Biopharmaceutical Suzhou

TitlePiperidine dione compounds, their preparation methods and uses

Family ID95204322

Family members2

Filing year2024

Publication date2025-12-26

JurisdictionCN

Compounds10

Activity records26

Assays3

Activity compounds and values

Activity records

26 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
IC50	-	<	10	nM	-	—	GSPT1	-	NCI-N87	PGDB_A010786	PGDB_C001022	PGDB_AS002207	View
IC50	-	=	10-30	nM	-	—	GSPT1	-	BT-474	PGDB_A011867	PGDB_C001024	PGDB_AS001477	View
IC50	-	<	10	nM	-	—	GSPT1	-	NCI-N87	PGDB_A014830	PGDB_C001023	PGDB_AS002207	View
IC50	-	=	10-30	nM	-	—	GSPT1	-	NCI-N87	PGDB_A021298	PGDB_C001025	PGDB_AS002207	View
IC50	-	=	10-30	nM	-	—	GSPT1	-	BT-474	PGDB_A027931	PGDB_C001019	PGDB_AS001477	View
IC50	-	<	10	nM	-	—	GSPT1	-	NCI-N87	PGDB_A031605	PGDB_C001020	PGDB_AS002207	View
IC50	-	=	10-30	nM	-	—	GSPT1	-	NCI-N87	PGDB_A032425	PGDB_C001026	PGDB_AS002207	View
IC50	-	=	10-30	nM	-	—	GSPT1	-	NCI-N87	PGDB_A035558	PGDB_C001019	PGDB_AS002207	View
IC50	-	<	10	nM	-	—	GSPT1	-	BT-474	PGDB_A036830	PGDB_C001022	PGDB_AS001477	View
IC50	-	>	150	nM	-	—	GSPT1	-	THLE-2	PGDB_A038764	PGDB_C001020	PGDB_AS000263	View
IC50	-	<	10	nM	-	—	GSPT1	-	BT-474	PGDB_A043615	PGDB_C001018	PGDB_AS001477	View
IC50	-	>	150	nM	-	—	GSPT1	-	THLE-2	PGDB_A049141	PGDB_C001019	PGDB_AS000263	View
IC50	-	=	10-30	nM	-	—	GSPT1	-	BT-474	PGDB_A050080	PGDB_C001025	PGDB_AS001477	View
IC50	-	<	10	nM	-	—	GSPT1	-	THLE-2	PGDB_A051133	PGDB_C001018	PGDB_AS000263	View
IC50	-	<	10	nM	-	—	GSPT1	-	NCI-N87	PGDB_A052224	PGDB_C001018	PGDB_AS002207	View
IC50	-	<	10	nM	-	—	GSPT1	-	BT-474	PGDB_A053304	PGDB_C001021	PGDB_AS001477	View
IC50	-	=	10-30	nM	-	—	GSPT1	-	NCI-N87	PGDB_A056274	PGDB_C001027	PGDB_AS002207	View
IC50	-	<	10	nM	-	—	GSPT1	-	BT-474	PGDB_A060537	PGDB_C001020	PGDB_AS001477	View
IC50	-	<	10	nM	-	—	GSPT1	-	BT-474	PGDB_A062808	PGDB_C001023	PGDB_AS001477	View
IC50	-	=	10-30	nM	-	—	GSPT1	-	BT-474	PGDB_A066198	PGDB_C001026	PGDB_AS001477	View

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