Activity record

PGDB_A028032

Assay: viabilityTarget: KRASQC: standardized
Activity overview

IC50 = 1.361 nM

TargetKRAS
Cell lineHPAC
Time5-day treatment
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS000104
PatentWO2025214350A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011631
Compound IDPGDB_C011631
CompoundRef.2
Source record IDPGDB_C011631
InChIKeyKVUWOWQNBGKSDJ-ZCBHDBAISA-N

Assay context

Assay IDPGDB_AS000104
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time5-day treatment
Detection target% Cell viability
TargetKRAS
E3Not specified
Cell lineHPAC
OrganismHomo sapiens

Source evidence

Patent IDWO2025214350A1
Compound location

Ref.2

Ref.2 enlarged structureRef.2 location on patent page 220
Activity table
Page 226 · table single