Activity record

PGDB_A028240

Assay: viabilityTarget: GSPT1QC: manual_curated
Activity overview

IC50 = > 20-30 nM

TargetGSPT1
Cell lineMV-4-11
Time72 h
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS002456
PatentCN120289428A
QC statusmanual_curated
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000707
Compound IDPGDB_C000707
Compound实施例14
Source record IDPGDB_C000707
InChIKeyVNHRALYRKPZUDZ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002456
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineMV-4-11

Source evidence

Patent IDCN120289428A
Compound location

实施例14

实施例14 enlarged structure实施例14 location on patent page 42
Activity table
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