Activity record

PGDB_A028248

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

DC50 = 0.0695 uM

TargetGSPT1
Cell line293A
Time6 h
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001164
PatentCN121591645A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001077
Compound IDPGDB_C001077
Compound8;8;化合物8
Source record IDPGDB_C001077
InChIKeyCIFUIUGKVIVJIV-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001164
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time6 h
Detection targetprotein_degradation
TargetGSPT1
E3Not specified
Cell line293A

Source evidence

Patent IDCN121591645A
Compound location

8;8;化合物8

8;8;化合物8 enlarged structure8;8;化合物8 location on patent page 3
Activity table
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