Activity record

PGDB_A028287

Assay: % DegradationTarget: POLR2AQC: ambiguous
Activity overview

IC50 = 0.3-3 uM

TargetPOLR2A
Assay / ReadoutIC50 / % Degradation
Assay IDPGDB_AS000589
PatentWO2025110815A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010969
Compound IDPGDB_C010969
Compound86
Source record IDPGDB_C010969
InChIKeyCFDSSRJCTKROHO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000589
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
TargetPOLR2A
E3Not specified

Source evidence

Patent IDWO2025110815A1
Compound location

86

86 enlarged structure86 location on patent page 121
Activity table
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