Assay

PGDB_AS000589

System: cell_basedTarget: POLR2A
Assay context summary

Assay context

109 activity records
Assay family% Degradation
Systemcell_based
ReadoutIC50
TargetPOLR2A
E3Not specified
Activity compounds and values

Activity records

109 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C010990
IC50-<=0.3uM-—POLR2A--WO2025110815A1PGDB_A007136PGDB_C010990PGDB_AS000589View
2D structure for PGDB_C010965
IC50-=0.3-3uM-—POLR2A--WO2025110815A1PGDB_A008267PGDB_C010965PGDB_AS000589View
2D structure for PGDB_C011002
IC50-<=0.3uM-—POLR2A--WO2025110815A1PGDB_A008324PGDB_C011002PGDB_AS000589View
2D structure for PGDB_C010921
IC50-<=0.3uM-—POLR2A--WO2025110815A1PGDB_A009103PGDB_C010921PGDB_AS000589View
2D structure for PGDB_C011000
IC50-<=0.3uM-—POLR2A--WO2025110815A1PGDB_A009351PGDB_C011000PGDB_AS000589View
2D structure for PGDB_C010929
IC50->3uM-—POLR2A--WO2025110815A1PGDB_A009975PGDB_C010929PGDB_AS000589View
2D structure for PGDB_C010974
IC50-=0.3-3uM-—POLR2A--WO2025110815A1PGDB_A010663PGDB_C010974PGDB_AS000589View
2D structure for PGDB_C010981
IC50-<=0.3uM-—POLR2A--WO2025110815A1PGDB_A012644PGDB_C010981PGDB_AS000589View
2D structure for PGDB_C010908
IC50-=0.3-3uM-—POLR2A--WO2025110815A1PGDB_A014416PGDB_C010908PGDB_AS000589View
2D structure for PGDB_C010968
IC50->3uM-—POLR2A--WO2025110815A1PGDB_A015207PGDB_C010968PGDB_AS000589View
2D structure for PGDB_C010896
IC50-=0.3-3uM-—POLR2A--WO2025110815A1PGDB_A016080PGDB_C010896PGDB_AS000589View
2D structure for PGDB_C010923
IC50-=0.3-3uM-—POLR2A--WO2025110815A1PGDB_A016437PGDB_C010923PGDB_AS000589View
2D structure for PGDB_C010976
IC50-<=0.3uM-—POLR2A--WO2025110815A1PGDB_A017097PGDB_C010976PGDB_AS000589View
2D structure for PGDB_C010911
IC50-<=0.3uM-—POLR2A--WO2025110815A1PGDB_A018477PGDB_C010911PGDB_AS000589View
2D structure for PGDB_C010985
IC50-<=0.3uM-—POLR2A--WO2025110815A1PGDB_A018824PGDB_C010985PGDB_AS000589View
2D structure for PGDB_C010971
IC50-=0.3-3uM-—POLR2A--WO2025110815A1PGDB_A019829PGDB_C010971PGDB_AS000589View
2D structure for PGDB_C010905
IC50-<=0.3uM-—POLR2A--WO2025110815A1PGDB_A020735PGDB_C010905PGDB_AS000589View
2D structure for PGDB_C010973
IC50-=0.3-3uM-—POLR2A--WO2025110815A1PGDB_A022539PGDB_C010973PGDB_AS000589View
2D structure for PGDB_C010899
IC50-=0.3-3uM-—POLR2A--WO2025110815A1PGDB_A023321PGDB_C010899PGDB_AS000589View
2D structure for PGDB_C010978
IC50-<=0.3uM-—POLR2A--WO2025110815A1PGDB_A023409PGDB_C010978PGDB_AS000589View
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