Activity record

PGDB_A029078

Assay: bindingTarget: CRBNQC: standardized
Activity overview

Ki = 12.2 uM

TargetCRBN
E3 ligaseCRBN
Time60 min
Assay / Readoutfluorescence / Ki
Assay IDPGDB_AS002388
PatentUS12110292B2
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008992
Compound IDPGDB_C008992
Compound5;5;5
Source record IDPGDB_C008992
InChIKeyAYCPJKZUTZCXTH-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002388
Assay familybinding
Assay systembiochemical
ReadoutKi
Technologyfluorescence
Treatment time60 min
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDUS12110292B2
Compound location

5;5;5

5;5;5 enlarged structure5;5;5 location on patent page 27
Activity table
Page 102 · table start
Page 103 · table end