Activity record

PGDB_A029177

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

IC50 = 1 uM

TargetGSPT1
Cell lineHEK293
Time6 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS002511
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008019
Compound IDPGDB_C008019
Compound115;115;115
Source record IDPGDB_C008019
InChIKeyDNFMSGFTURZTLS-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002511
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time6 h
TargetGSPT1
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

115;115;115

115;115;115 enlarged structure115;115;115 location on patent page 28
Activity table
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